Micro-liquid flow is widely used in microreactors,which has the advantages of high heat and mass transfer efficiency,high throughput,integration,and easy control.Micro-liquid flowmeter can achieve accurate control of samples.At meager flow rates(μL/min to nL/min),however,micro-liquid flowmeter has problems such as incomplete measurement standards and difficult calibration.Several calibration techniques used in the field of micro-liquid flow measurement are summarized,including the mass method and volumetric method.The calibration range and uncertainty of these techniques are given according to the existing research.The analysis shows that the current mass method calibration technology is still insufficient in the application of micro-liquid flow,and the influence of multiple action mechanisms needs to be further studied.The volumetric method can be achieved by different means.Although this method is still in the exploration stage,it is expected to become a more promising method in the future.Finally,combined with the development of micro-liquid flow measurement technology and the construction of an advanced measurement system,the development prospect of micro-liquid flow measurement is forecasted.