Research progress on the regulation of signal molecule AI-2 during sludge granulation
Quorum sensing is a communication mechanism widely existing in microorganisms.Autoinducer-2(AI-2),a kind of quorum sensing signaling molecule for interspecies communication,has received increasing attention for its role in regulating bacterial gene expression and aggregation.Granular sludge,as a kind of microbial aggregates,has been widely concerned and studied because of its advantages such as high microbial population,good settleability and high resistance to loads.A large number of studies have shown that AI-2 mediated quorum sensing plays an important role in the process of sludge granulation.This paper reviewed the formation of AI-2 signaling molecules and the mechanism of AI-2 mediated quorum sensing,the detection methods of AI-2,the influencing factors in the production of AI-2 and its distribution in granular sludge,summarized the regulatory role of AI-2 in the process of granulation,and finally provided an outlook of the research of AI-2 mediated quorum sensing in granular sludge.The aim is to provide theoretical references for the in-depth understanding of the regulation effect of quorum sensing on sludge granulation as well as for promoting the engineering application of sludge granulation.
国家科技期刊平台
NSTL
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