Optimization of gardenia and poria cocos tablet candy extractionprocess by box-behnken experimental design with multi-index comprehensive scoring method
The content of geniposide in the extract and the dry paste rate were used as the investigation indexes.On the basis of single factor experiment,the direct reflux extraction method was used,and the multi-index comprehensive scoring method combined with Box-Behnken response surface method was used to investigate the effects of ethanol concentration,extraction time and solvent doubling on the extraction process.The results showed that the optimal extraction process was 75％ethanol,120 min extraction time and 17 times solvent doubling.The process is reasonable and feasible,and the extraction rate of active components is high.It is suitable for large-scale production and provides a scientific basis for industrial production.
The tablet candy of gardenia and poria cocosMulti-index comprehensive scoring methodBox-Behnken experimental designExtraction technology
万方数据
维普
