Taking the first trial production of 12Cr5Mo heat-resistant steel pressure vessel by a certain unit as an example,this paper introduces the quality control in the process of the manufacturing supervisory inspection of heat-resistant steel pressure vessel,focusing on the control of the warehousing inspection of 12Cr5Mo materials,the control of welding related processes,and the process control of heat treatment.By analyzing the welding structure between different pressure components on the pressure vessel body and the material properties of 12Cr5Mo,according to the provided welding procedure qualification,welder qualification items,and heat treatment process,it is found that the qualification of welders in relevant parts is not covered.Through optimizing the heat treatment process and selecting the appropriate welding technology evaluation and welder,the NDT and pressure test were successfully passed.