At present,HP40 material is widely used for reformer tubes in chemical industrial plants in China.In the process of high-temperature service,this material degrades and damages after a long time of high-temperature creep.The damage will gradually develop into a crack,which eventually leads to the rupture of the furnace tube.Relevant scholars at home and abroad have carried out relevant research on the high-temperature creep damage life assessment of reformer tubes,and gradually formed the Larson Miller parameter method.However,this method lacks consideration of the uncertainty of working load.This paper refers to the previous research methods,combined with the creep damage calculation method.Finally,the analysis and evaluation of the remaining life of reformer tubes under multiple working conditions are completed.