Process Improvement of Chiral Secondary Alcohols by Enzyme Catalysis Based on TRIZ Theory
Chiral secondary alcohols are always considered important chiral intermediates in the synthesis of chemical products.An important step in the synthesis of chiral compounds is the preparation of their optically pure enantiomers.The preparation process for chiral secondary alcohols is plagued by low yield,low enantiomer purity,and high production costs.To solve these issues,this study applied the logic of problem identification,analysis,and resolution to optimize the preparation process using TRIZ theory.The study suggested a one-pot method that improved enantiomer purity and yield for the chiral secondary alcohols that were produced.As a result,the cost of production is effectively decreased.This work offers theoretical direction and a useful practical reference for future optimization of the chiral secondary alcohol preparation process.
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