Organic Chemistry Experiment is a required course for undergraduates majoring in chemistry and related majors,which is highly practical.To cultivate students'divergent thinking and innovative ability through the course of Organic Chemistry Experiment is an important way to cultivate compound talents.Based on the author's exploration in the teaching and practice of the Organic Chemistry Experiment course,this paper makes an exploratory reform of the organic chemistry experiment course from the aspects of experimental design,assessment mechanism and application,aiming at further cultivating students'innovation ability and improving teaching quality.