The gelatin hollow capsules produced by enzymatic method were compared with the gelatin hollow capsules produced by alkaline method and acid method,the application studies were carried out by friability,disintegration time and dissolution.The results showed that the brittleness of the hollow gelatin capsules prepared by enzymatic method was almost the same as that of the hollow gelatin capsules prepared by alkaline method,and was better than that of the hollow gelatin capsules prepared by acid method,the advantage of low viscosity and high freezing strength gelatin is obvious,and the three kinds of hollow gelatin capsules have the same technology.
关键词
酶法明胶/明胶空心胶囊/脆碎度/崩解时限/溶出度
Key words
enzymatic gelatin/gelatin hollow capsule/brittleness/collapse time limit/dissolution