化工时刊2024，Vol.38Issue(2) ：15-16,24.DOI:10.16597/j.cnki.issn.1002-154x.2024.02.004

用于提高注射用替考拉宁澄清度和稳定性的方法

A Method for Improving the Turbidity and Stability of Teicoranine for Injection

邹琦 王乐乐 黄萍
化工时刊2024，Vol.38Issue(2) ：15-16,24.DOI:10.16597/j.cnki.issn.1002-154x.2024.02.004
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用于提高注射用替考拉宁澄清度和稳定性的方法

A Method for Improving the Turbidity and Stability of Teicoranine for Injection

邹琦 1王乐乐 1黄萍1
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作者信息

  • 1. 浙江医药股份有限公司新昌制药厂,新昌 312500
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摘要

为了制备注射用替考拉宁等渗组合物,需考察药液的澄清度及稳定性.作者采用分别加入不同比例的氯化钠和葡萄糖的方法,制备含替考拉宁的等渗组合物,考察其澄清度和稳定性.结果表明,在保持等渗的前提下,随着加入葡萄糖的量逐渐提高,氯化钠的量逐渐减少,组合物的澄清度明显提高,组合物的稳定性不变.

Abstract

Teicoplanin isotonic for injection was prepared and its turbidity and stability were investigated.The isotonic composition containing teicoplanin was prepared by adding sodium chloride and glucose.Under the condition of maintaining isotonic,as the amount of glucose increased gradually,the amount of sodium chloride decreased gradually,the clarity of the composition increased obviously,and the stability of the composition remained unchanged.The composition prepared by this method has good turbidity and stability.

关键词

注射用替考拉宁/澄清度/稳定性/等渗

Key words

teicoplanin for injection/turbidity/stability/iso-osmia

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出版年

2024
化工时刊
东南大学

化工时刊

影响因子：0.333
ISSN：1002-154X
参考文献量4
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