Hydrophilic Modification and Performance Characterization of Rigid Gas Permeable Contact Lenses Based on Copolymerization Method
Rigid gas permeable contact lenses(RGP)play an important role in vision correction and the treatment of specific ophthalmic diseases due to their high oxygen permeability and safety.However,the hydrophobicity of the RGP material itself,which leads to a range of ocular discomfort,has limited the widespread use of RGP.In this study,the hydrophilic monomers DMA and NVP copolymerization were used to hydrophilically modify RGP materials,in which the addition of 9％DMA and 13％NVP could effectively reduce the contact angle from 100° to about 83° and 85°,respectively,the hardness could be increased from 78 HD to 85 HD,and the light transmittance was higher than 95％,and the oxygen transmittance of DMA-9 was 215 barrers,and that of NVP-13 was 192 barrers.Further evaluation in terms of extraction rate and in vitro cytotoxicity confirmed that DMA-9 and NVP-13 was biocompatible with RGP.The feasibility of hydrophilic modification of RGP materials using hydrophilic monomer copolymerization was demonstrated.
N,N-DimethylacrylamideN-Vinylpyrrolidonehydrophilic modificationrigid gas permeable contact lenses
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