首页|膜技术在杜仲有效成分分离纯化中的应用研究进展

膜技术在杜仲有效成分分离纯化中的应用研究进展

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杜仲是我国传统名贵药材,具有抗肿瘤、抗氧化、抗骨质疏松、消炎和调节血压等医疗保健作用,其中的绿原酸、黄酮等小分子具有较高的药用价值.然而,传统中药存在成分复杂、生产工艺落后的问题.膜分离技术具有分离效率高、能耗低、操作简单、无二次污染等特点,在中药的分离纯化中展现出良好的应用前景.杜仲是中国特有的药材,国际上对于膜分离杜仲有效成分研究较少,国内对其研究还处在起步阶段.本文分析了膜的分离机理,综述了膜在杜仲有效成分分离纯化中的应用进展,讨论了膜分离过程的影响因素,最后进一步指出膜技术用于中药有效成分分离纯化时在膜材料及膜污染等方面存在的问题,并对未来膜技术在低成本专用膜材料及系统开发和膜污染控制方面的研究进行了展望,以期为杜仲有效成分的高效利用提供参考.
Application of membranes for separation and purification of Eucommia ulmoides active ingredients
Eucommia ulmoides is a traditional and precious medicinal material in China,which has the functions of anti-tumor,anti-oxidation,anti-osteoporosis,anti-inflammatory and blood pressure regulation.Its active ingredients such as chlorogenic acid and flavonoids have high medicinal value.However,the traditional Chinese medicine has complex ingredients and backward production technology.Membrane separation technology has the characteristics of high separation efficiency,low energy consumption,simple operation and no secondary pollution,and shows a good application prospect in the separation and purification of traditional Chinese medicine.As Eucommia ulmoides is a unique medicinal material in China,there are few studies on membrane separation of Eucommia ulmoides active components in the world,and the domestic research on it is still in the initial stage.It is hoped that the extraction,detection,separation and purification methods of Eucommia ulmoides active components will be reviewed to provide theoretical support for the multipolar utilization of eucommia active components.In this paper,the separation mechanism of membrane was analyzed,the application of membrane in the separation and purification of Eucommia ulmoides was reviewed,and the factors affecting the separation process were discussed.Finally,the problems of membrane materials and membrane pollution in the separation and purification of Eucommia ulmoides active components were further pointed out,and the future research of membrane technology in the development of low-cost special membrane materials and systems and membrane pollution control was prospected.

chlorogenic acidmembranetraditional Chinese medicinepurificationseparationEucommia ulmoides

顾天宇、陈献富、王思琪、徐鹏、邱鸣慧、范益群

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南京工业大学化工学院,材料化学工程国家重点实验室,江苏南京 211816

绿原酸 中药 纯化 分离 杜仲

2024

化工学报
中国化工学会 化学工业出版社

化工学报

CSTPCD北大核心
影响因子:1.26
ISSN:0438-1157
年,卷(期):2024.75(11)