The renewable methanol is one of important ways in achieving sustainable development.The volatility and intermittency of renewable energy lead to frequent fluctuations in the operating conditions of the carbon dioxide hydrogenation to methanol process.To adapt to the fluctuations in renewable energy,it is necessary to enhance the flexibility of the methanol production system.In this work,a renewable methanol production system operating window regulation strategy for selecting appropriate equipment is proposed.The equipment database is established through the design and analysis of the operating window characteristics of key equipment under process conditions and operational constraints,and the operating window of the production system is expanded by optimizing the equipment set through the regulation strategy.The results indicated that the proposed method can effectively regulate the operating window of the methanol production system by maximizing the upper limit,minimizing the lower limit,and maximizing the range of operating window,and determine the optimal equipment combination and design scheme according to the application scenarios.These results are expected to provide guidance for flexibility improvement of methanol production system adapted to the fluctuations of renewable energy.