Research progress of polymer antibacterial materials
In the face of escalating antibiotic resistance due to widespread usage,the persistent emergence of multidrug-resistant pathogens is a formidable threat to human health.Traditional low-molecular-weight antibacterial agents,when used alone,often fall short of achieving desired efficacy,hampered by issues of biocompatibility and stability.The introduction of polymeric antibacterial materials,characterized by diverse synthesis strategies and higher efficiency,offers a promising approach to combatting pathogenic microorganisms.Contrasted with their low-molecular-weight organic or inorganic antibacterial materials,these materials demonstrate commendable biocompatibility,controllable functional attributes,and a more extensive range of structural designs,enabling inhibitory and bactericidal effects through diverse mechanisms.Their widespread adoption is observed in treating drug-resistant bacterial infections,formulating advanced wound dressings,targeted antibacterial interventions,and developing antibacterial coatings.This discourse provided a comprehensive classification and summary of existing polymeric antibacterial materials,considering synthesis strategies and mechanisms of action.It also outlined current challenges in their development and offered a forward-looking perspective on future directions,with the overarching goal of leveraging the intrinsic strengths of polymeric antibacterial materials for broader application.
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