摘要
目的：评价盐酸度洛西汀治疗惊恐障碍的疗效和安全性。方法符合CCMD-3诊断标准的惊恐障碍患者60例，治疗组(n=30)口服度洛西汀60 mg/d；对照组(n=30)口服草酸艾司西酞普兰20 mg/d，疗程均6周；以17项汉密尔顿焦虑量表(HAMA17)进行疗效评价；以副反应量表(TESS)和心电图检查等评价安全性。结果两组治疗总有效率差异无统计学意义，不良反应差异无统计学意义，评分2~6周差异有统计学意义(P＜0.05)。盐酸度洛西汀治疗效果与草酸艾司西酞普兰治疗效果差异有统计学意义。结论度洛西汀治疗惊恐障碍安全有效，见效快，具有临床应用的价值。
Abstract
Objective to evaluate the effect of hydrochloric acid degree, treatment of panic disorder, and security. Methods accord with CCMD 3 diagnostic criteria of 60 patients with panic disorder, treatment group(n=30) oral duloxetine 60 mg per day;The con-trol group(n=28) oral escitalopram oxalate citalopram 20 mg a day, a course 6 weeks;With 17 Hamilton anxiety scale (HAMA17) curative effect evaluation; With symptoms scale (TESS) and electrocardiogram examination evaluation of safety. Results duloxetine and escitalopram oxalate citalopram for panic disorder has significant curative effect (P<0.01). Curative effect is no significant dif-ference between the two groups have no statistical significance (P>0.05). No significant difference side effects. Conclusion duloxe-tine panic disorder is safe and effective treatment, work fast, side effects.
NETL
NSTL
维普
万方数据