首页|慢阻肺急性加重期伴呼吸衰竭的BIPAP结合硫酸特布他林雾化溶液吸入治疗效果及对免疫功能影响

慢阻肺急性加重期伴呼吸衰竭的BIPAP结合硫酸特布他林雾化溶液吸入治疗效果及对免疫功能影响

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目的 探究慢性阻塞性肺疾病(简称慢阻肺)急性加重期伴呼吸衰竭患者采用双水平气道正压通气(Bi-level Positive Airway Pressure,BIPAP)结合硫酸特布他林雾化溶液吸入的临床疗效.方法 选取2022年1-12月江苏省沭阳仁慈医院收治的60例慢阻肺急性加重期伴呼吸衰竭患者为研究对象,依据随机数字表法分为对照组和观察组,各30例.对照组采用BIPAP治疗,观察组采用硫酸特布他林+BIPAP治疗,比较两组患者的免疫功能水平、血气指标、肺功能指标.结果 观察组患者的各项免疫功能水平和血气指标水平优于对照组,差异有统计学意义(P均<0.05).观察组患者的肺功能指标高于对照组,差异有统计学意义(P<0.05).结论 慢阻肺急性加重期伴呼吸衰竭疾病病情重,危及患者机体健康,采用BIPAP与硫酸特布他林联用,可快速恢复免疫功能,改善血气,并提高肺功能.
Effects of BIPAP Combined with Terbutaline Sulfate Aerosol Inhalation on Respiratory Failure and Immune Function in Patients with Acute Exac-erbation of COPD
Objective To explore the clinical effect of Bi-level level positive airway pressure(BIPAP)combined with terbutaline sulfate aerosol inhalation in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD)and respiratory failure.Methods Sixty patients with acute exacerbation of COPD and respiratory failure admit-ted to Shuyang Renci Hospital in Jiangsu Province from January to December 2022 were selected as the study sub-jects.They were randomly divided into a control group and an observation group,with 30 cases in each group,using a random number table method.The control group received BIPAP treatment,while the observation group received ter-butaline sulfate + BIPAP treatment.The immune function levels,blood gas indexes,and lung function indexes of the two groups of patients were compared.Results The levels of various immune functions and blood gas indexes in the ob-servation group were better than those in the control group,and the differences were statistically significant(all P<0.05).The lung function indexes of the observation group was higher than those of the control group,and the differ-ence was statistically significant(P<0.05).Conclusion The acute exacerbation of COPD accompanied by respiratory failure is serious and endangers the health of patients.BIPAP combined with terbutaline sulfate can quickly restore immune function,improve blood gas and lung function.

Chronic obstructive pulmonary diseaseRespiratory failureTerbutaline sulfateImmune functionBi-level positive airway pressure

杜水英

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江苏省沭阳仁慈医院呼吸科,江苏沭阳 223600

慢性阻塞性肺疾病 呼吸衰竭 硫酸特布他林 免疫功能 双水平气道正压通气

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(1)
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