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化痰祛瘀通脉汤对老年急性心衰患者心肌损伤的影响

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目的 探究化痰祛瘀通脉汤对老年急性心力衰竭(简称心衰)患者心肌损伤的影响.方法 方便选取2021年8月—2022年10月期间山东省泰山医院、烟台山医院收治的92例老年急性心衰患者为研究对象,按照随机抽签法分为对照组与观察组,各46例,对照组进行常规抗心衰治疗,观察组在常规对症治疗基础上采取化痰祛瘀通脉汤,对比两组临床总有效率、心肌损伤状况、用药安全性.结果 用药两周后,观察组临床总有效率(95.65%)较对照组(80.43%)高,差异有统计学意义(χ2=5.059,P<0.05).观察组血清氨基末端B型脑钠肽前体、B型脑钠肽、血清肌钙蛋白T水平较对照组低,差异有统计学意义(P均<0.05).两组不良反应总发生率比较,差异无统计学意义(P>0.05).结论 化痰祛瘀通脉汤的作用效果较理想,有助于改善老年急性心衰患者心肌损伤程度,缓解症状,且安全可靠.
Effects of Huatan Quyu Tongmai Decoction on Myocardial Injury in El-derly Patients with Acute Heart Failure
Objective To investigate the effect of Huatan Quyu Tongmai decoction on myocardial injury in elderly pa-tients with acute heart failure(referred to as heart failure).Methods Ninety-two elderly patients with acute heart fail-ure admitted to Shandong Taishan Hospital and Yantaishan Hospital between August 2021 and October 2022 were conveniently selected as study subjects and divided into 46 cases each in the control group and the observation group according to the method of random draw.The control group was treated with conventional anti-heart failure therapy,and the observation group was treated with Huatan Quyu Tongmai decoction on the basis of conventional symptom-atic therapy.The clinical total effective rate,myocardial injury and drug safety were compared between the two groups.Results After two weeks of treatment,the total effective rate of the observation group(95.65%)was higher than that of the control group(80.43%),and the difference was statistically significant(χ2=5.059,P<0.05).The levels of amino terminal B-type brain natriuretic peptide precursor,B-type brain natriuretic peptide and troponin T in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The effect of Huatan Quyu Tongmai decoction is more satisfactory,which helps to improve the degree of myocardial injury and alleviate the symptoms of elderly patients with acute heart failure,and is safe and reliable.

Elderly peopleAcute heart failureHuatan Quyu Tongmai decoctionMyocardial injury

王平、王立、寇伟

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山东省泰山医院心内科,山东泰安 271000

山东烟台山医院ICU,山东烟台 264000

山东省泰山医院老年科,山东泰安 271000

老年人 急性心衰 化痰祛瘀通脉汤 心肌损伤

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(1)
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