首页|内镜下黏膜切除术对结肠息肉患者炎症因子、预后恢复的影响

内镜下黏膜切除术对结肠息肉患者炎症因子、预后恢复的影响

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目的 探讨内镜下黏膜切除术对结肠息肉患者炎症因子、预后恢复的影响.方法 方便选取2022年3月—2023年3月烟台海港医院收治的102例结肠息肉患者为研究对象.按照不同的治疗方案分成对照组和观察组,采取高频电切术治疗的51例患者纳入对照组,采取内镜下黏膜切除术的51例患者纳入观察组.比较两组的治疗效果、围术期指标、炎症因子、并发症.结果 观察组总有效率为 98.04%,高于对照组的78.43%,差异有统计学意义(χ2=9.444,P=0.002).观察组手术时间、住院时间、术后胃肠功能恢复时间均比对照组短,差异有统计学意义(P均<0.05).术前,两组白细胞介素-6、白细胞介素-8、白细胞介素-1β比较,差异无统计学意义(P均>0.05);与术前相比,术后1 d两组上述炎性因子水平均上升明显,且观察组术后1 d上述炎性因子水平均比对照组低,差异有统计学意义(P均<0.05).观察组并发症发生率比对照组更低,差异有统计学意义(P<0.05).结论 采用内镜下黏膜切除术治疗结肠息肉患者,能够有效抑制炎症反应,疗效显著,安全性高,可促进患者预后恢复.
Effect of Endoscopic Mucosal Resection on Inflammatory Factors and Prognostic Recovery in Patients with Colonic Polyps
Objective To explore the effects of endoscopic mucosal resection on inflammatory factors and prognostic recovery in patients with colonic polyps.Methods It is convenient to select 102 patients with colon polyps admitted to Yantai Haigang Hospital from March 2022 to March 2023 as the study subjects.According to different treatment op-tions,they were divided into control group and observation group.51 patients treated with high-frequency electrotomy were included in the control group,and 51 patients treated with endoscopic mucosal resection were included in the ob-servation group.The therapeutic effect,perioperative indicators,inflammatory factors and complications were com-pared between the two group.Results The total effective rate of the observation group was 98.04%,which was higher than the control group's 78.43%,and the difference was statistically significant(χ2=9.444,P=0.002).The observation group had shorter surgical time,shorter hospital stay,and shorter postoperative gastrointestinal function recovery time compared to the control group,and the differences were statistically significant(all P<0.05).Interleukin-6,interleu-kin-8,and interleukin-1β compared in two groups of patients before surgery,the difference was not statistically sig-nificant(all P>0.05).Compared with preoperative conditions,the levels of inflammatory factors mentioned above in both groups of patients increased significantly 1 d after surgery,and the levels of inflammatory factors mentioned above in the observation group were lower than those in the control group 1 d after surgery,and the differences were statistically significant(all P<0.05).The incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of endoscopic mucosal re-section for the treatment of patients with colonic polyps can effectively inhibit the inflammatory response,with remark-able efficacy and high safety,and can promote the prognosis of patients'recovery.

Endoscopic mucosal resectionColonic polypsInflammatory factorPrognostic recoveryComplications

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烟台海港医院消化内科,山东烟台 264002

内镜下黏膜切除术 结肠息肉 炎症因子 预后恢复 并发症

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(2)
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