Effect of Dezocine on Postoperative Pain Levels after Combined Spinal and Epidural Anesthesia in Patients with Lower Extremity Fractures
Objective To study the effect of dezocine on postoperative pain in patients with lower limb fracture under combined spinal and epidural anesthesia.Methods A total of 74 patients with lower extremity fracture who underwent combined lumbar and epidural anesthesia in Longyan People's Hospital of Fujian Province from May 2021 to Febru-ary 2023 were conveniently selected as the study objects,and were divided into control group and observation group according to random number table method,with 37 cases in each group.The control group was given lumboepidural anesthesia,and the observation group was given dezocine intravenous injection based on the anesthesia conditions of the control group.The basic signs indexes,postoperative sedation depth,pain degree and analgesic safety of the two groups were compared at different time points.Results The systolic pressure(SBP),diastolic pressure(DBP)and heart rate in the observation group were lower than those in the control group at the time of skin resection and 1 h after sur-gery,and the differences were statistically significant(all P<0.05).At 1,3,6 and 12 h after operation,the Visual Ana-logue Scale(VAS)scores of the observation group were lower than those of the control group,the scores of Observer's Assessment of Alertness/Sedation(OAA/S)were higher than those of control group,and the differences were statisti-cally significant(all P<0.05).The incidence of adverse reactions in observation group(8.11%)was lower than that in control group(27.03%),and the difference was statistically significant(χ2=4.572,P=0.032).Conclusion Combined epidural anesthesia with dezocine can effectively improve the vital signs of patients with lower extremity fracture,re-duce the degree of postoperative pain,and reduce the occurrence of adverse reactions.
Lower extremity fractureDezocineCombined spinal and epidural anesthesiaPostoperative pain levelAnalgesic safety
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维普
