首页|老年翼状胬肉患者翼状胬肉切除与角膜缘干细胞移植联合治疗的疗效分析

老年翼状胬肉患者翼状胬肉切除与角膜缘干细胞移植联合治疗的疗效分析

扫码查看
目的 分析翼状胬肉切除联合角膜缘干细胞移植的临床疗效.方法 回顾性选取2021年1月—2023年1月尤溪县总医院收治的80例老年翼状胬肉患者的临床资料,40例采用单纯翼状胬肉切除术治疗患者作为对照组,40例加用角膜缘干细胞移植治疗患者作为观察组.比较两组治疗效果.结果 治疗后,观察组泪膜破裂时间、基础泪液分泌测定高于对照组,角结膜荧光素染色评分低于对照组,差异有统计学意义(P均<0.05).治疗后3、7 d,观察组结膜水肿、结膜充血评分低于对照组,差异有统计学意义(P均<0.05).观察组视觉功能指标改善优于对照组,差异有统计学意义(P<0.05).观察组并发症发生率为12.50%,复发率为5.00%,低于对照组,差异有统计学意义(χ2=4.588、5.165,P均<0.05).结论 翼状胬肉切除联合角膜缘干细胞移植可有效改善老年翼状胬肉患者泪膜稳定性和视觉功能,降低并发症发生率及复发率.
Effect of Pterygium Excision Combined with Limbal Stem Cell Transplan-tation in Elderly Patients with Pterygium
Objective To analyze the clinical effect of pterygium excision combined with limbal stem cell transplanta-tion.Methods The clinical data of 80 cases of elderly pterygium patients admitted to Youxi County General Hospital from January 2021 to January 2023 were retrospectively selected,40 patients treated with simple pterygium excision as the control group,and 40 patients treated with the addition of corneal limbal stem cell transplantation as the obser-vation group.The treatment effects of the two groups were compared.Results After treatment,the tear film rupture time and basal tear secretion measurement of the observation group were higher than that of the control group,and the corneal conjunctival fluorescein staining score was lower than that of the control group,and the difference was statisti-cally significant(all P<0.05).Conjunctival edema and conjunctival congestion scores of the observation group were lower than those of the control group at 3 d and 7 d after treatment,and the differences were statistically significant(all P<0.05).The improvement of visual function indexes in the observation group was better than that in the control group,and the difference was statistically significant(P<0.05).The complication rate of the observation group was 12.50%and the recurrence rate was 5.00%,which were lower than those of the control group,and the differences were statistically significant(χ2=4.588,5.165,both P<0.05).Conclusion Pterygium excision combined with limbal stem cell transplantation can effectively improve tear film stability and visual function in elderly patients with pterygium,and reduce the incidence of complications and recurrence.

Pterygium of elderlyLimbal stem cell transplantationTear film stabilityVisual functionRecurrence rate

宋琳琳、谢秀缎、郑庆炜

展开 >

尤溪县总医院眼耳鼻喉科,福建三明 365100

老年翼状胬肉 角膜缘干细胞移植 泪膜稳定性 视觉功能 复发率

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(3)
  • 14