Feasibility Analysis of Mizolastine in the Treatment of Acute and Chronic Urticaria Complicated with Allergic Rhinitis
Objective To analyze the feasibility of mizolastine in the treatment of acute and chronic urticaria compli-cated with allergic rhinitis.Methods The clinical data of 100 patients with acute and chronic urticaria and allergic rhi-nitis admitted to the otolaryngology department of Linqu County People's Hospital,Shandong Province from February 2020 to February 2021 were retrospectively selected,according to the medication method,they were divided into mizo-lastine group,cetirizine group,50 cases each.Mizostine group oral cizostine and cetirizine group oral cetirizine.The number of wind groups,wind group diameter score,symptom score,quality of life,clinical efficacy,adverse effects,and recurrence of the two groups were compared.Results Before medication,there was no statistically significant differ-ence in the number of wind groups,wind group diameter score,itching,nasal itching,nasal congestion,sneezing,runny nose score between the two groups(all P＞0.05).After medication,the number of wind groups,wind diameter score,itching,nasal itching,nasal congestion,sneezing and runny nose of the two groups were lower than before medi-cation,and the mizolastine group was lower than cetirizine group,the differences were statistically significant(all P＜0.05).After medication,the quality of life score was higher than before medication,and the mizastine group was higher than cetirizine group,the difference was statistically significant(all P＜0.05).The overall response rate in mizos-tine group was 96.00%which was higher than 80.00%in cetirizine group,the difference was statistically significant(χ2=6.061,P＜0.05).The incidence of adverse reactions and recurrence in midazastine group were lower than those in cetirizine group,and the difference was statistically significant(both P＜0.05).Conclusion The feasibility of imidazoas-tine for acute and chronic urticaria complicated by allergic rhinitis is high.
Acute and chronic urticariaAllergic rhinitisCetirizineMizolastineQuality of lifeAdverse reaction
万方数据
维普
