Analysis of Influencing Factors on Death Outcome of Mechanical Ventila-tion in Patients with Severe Pulmonary Tuberculosis Complicated with COPD
Objective To investigate the effect of mechanical ventilation on death outcome in patients with severe pul-monary tuberculosis complicated with chronic obstructive pulmonary disease(COPD).Methods Retrospectively ana-lyzed the clinical data of 60 patients with severe tuberculosis combined with COPD admitted to the intensive care unit of the Department of Respiratory Medicine and the Department of Infectious Diseases in Zhangzhou Hospital Fujian Province from May 2020 to May 2021.All patients were treated with mechanical ventilation.According to the final outcome of the patients,40 successfully survived patients were included in the survival group,and 20 eventually died patients were included in the death group.The general data,treatment,laboratory indicators and CT images of the two groups were compared to analyze the risk factors of death.Results The of intensive care unit length of stay,intubation time,system or organ dysfunction,multidrug-resistant tuberculosis,ventilator-associated pneumonia,postventilator pneumothorax,pulmonary alveoli,and degree of lung damage between the two groups were compared,the differences were statistically significant(all P<0.05).Multifaceted Logistic regression analysis showed that hosplization time in in-tensive care unit,MDR-TB and ventilators associated pneumonia were independent risk factors for death after me-chanical ventilation in patients with severe pulmonary tuberculosis combined with COPD(OR=1.063,4.623,3.967,all P<0.05).Conclusion Multidrug-resistant pulmonary tuberculosis and ventilator-associated pneumonia are related fac-tors of death in patients with severe pulmonary tuberculosis combined with COPD after mechanical ventilation therapy.
Severe pulmonary tuberculosis complicated with COPDMechanical ventilationDeath outcomeFactor analysis
NETL
NSTL
万方数据
维普
