Clinical Effect of Heparin Sodium Combined with Dydrogesterone in the Treatment of Threatened Abortion
Objective To analyze the clinical effect of heparin sodium combined with dydrogesterone in the treatment of threatened abortion.Methods The medical records of 94 cases of women with preeclampsia in pregnancy seen by the Department of Obstetrics and Gynecology of Zaozhuang Maternal and Child Health Hospital from April 2021 to November 2022 were retrospectively selected and were divided into two groups according to the medication regimen,with 47 cases in each group.The reference group was given dedrogesterone tablets orally,and the study group was given low molecular weight heparin sodium injection.Uterine bleeding,absence time of lumbar and abdominal pain recovery time of progesterone,blood index,incidence of adverse reactions,fetal preservation rate,were compared.Results The survival rate of the study group(95.74%)was higher than that of the reference group(80.85%),and the difference was statistically significant(χ2=5.045,P=0.025).The disappearance time of uterine bleeding,lumbar and abdominal pain and the recovery time of progesterone in the study group were shorter than those in the reference group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the study group(4.25%)compared to the reference group(8.51%),the difference was not statistically significant(P>0.05).The improvement of fibrinogen,D-dimer and high sensitivity C-reactive protein in the study group after treatment was better than that in the reference group,the differences were statistically significant(all P<0.05).Conclusion The com-bined use of low molecular weight heparin sodium and dydrogesterone in the diagnosis and treatment of patients with threatened abortion is effective and has great clinical relevance.
NETL
NSTL
万方数据
维普
