Study on the Adverse Reactions of Different Routes of Administration of Azithromycin in the Treatment of Pediatric Bronchopneumonia
Objective To study the adverse reactions of different routes of administration of azithromycin in the treat-ment of pediatric bronchopneumonia.Methods A total of 100 children with bronchial pneumonia admitted to Jining Yanzhou District People's Hospital from February 2020 to February 2023 were randomly selected as the research ob-jects.According to different routes of administration of azithromycin,they were divided into oral sequential treatment group(sequential treatment group)and intravenous drip group,with 50 cases in each group.The therapeutic effect,lung function and adverse reactions were compared.Results There was no statistically significant difference in the to-tal effective rate of treatment between the two groups of children(P>0.05).The tidal volume,peak expiratory flow rate,forced expiratory volume at the first second,and forced vital capacity of children in the sequential treatment group were all higher than those in the intravenous infusion group,the differences were statistically significant(all P<0.05).The average levels of erythrocyte sedimentation rate,interleukin-6,procalcitonin,C-reactive protein,and serum amy-loid A were lower than those in the intravenous infusion group,the differences were statistically significant(all P<0.05).The total incidence of adverse reactions in the sequential treatment group was 16.00%,lower than 36.00%in the intravenous infusion group,and the difference was statistically significant(χ2=5.198,P<0.05).Conclusion Ad-verse effects of azithromycin intravenous drip followed by oral sequential therapy in the treatment of pediatric broncho-pneumonia were less than those of intravenous drip.
NETL
NSTL
万方数据
维普
