Analysis of the Effect of Mifepristone Cycle Therapy on Perimenopausal Abnormal Uterine Bleeding Patients
Objective To study the effect of mifepristone cycle therapy on patients with perimenopausal abnormal uter-ine bleeding(AUB).Methods 100 patients diagnosed as perimenopausal AUB by Zhangzhou China Merchants Eco-nomic and Technological Development Zone First Hospital from May 2021 to May 2023 were randomly selected as the study objects and the group design was completed based on the random number table method.50 cases in the control group received continuous oral mifepristone,and 50 cases in the observation group were treated with mifepristone cycle therapy.The efficacy,sex hormone levels,clinical indexes and drug safety of the two groups were compared.Results After 3 cycles of treatment,the therapeutic effect of the regimen in the observation group(96.00%)was higher than that in the control group(80.00%),and the difference was statistically significant(χ2=6.060,P<0.05).After treat-ment,the levels of various sex hormone indexes in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The hemoglobin value of the observation group was higher than that of the control group,and the endometrial thickness was lower than that of the control group,the differ-ences were statistically significant(both P<0.05).The incidence of adverse drug reactions between the two groups was similar,and there was no statistical significance difference(P>0.05).Conclusion The implementation of mifepristone cycle therapy for perimenopausal AUB patients can significantly enhance the effect of medication,regulate the level of sex hormones in the patient's body,increase hemoglobin value,and reduce the thickness of the endometrium,as well as ensure the safety of medication.
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维普
