Efficacy of Nifedipine Tablets+Magnesium Sulfate in the Treatment of Hy-pertensive Disease in Pregnancy and Its Effect on Patients'Blood Pressure and Prognosis
Objective To investigate the efficacy of nifedipine tablets combined with magnesium sulfate in the treat-ment of hypertension in pregnancy and it effect on patients'blood pressure and prognosis.Methods 70 patients with hypertension in pregnancy who were admitted to the Maternity Hospital of Nanjing Medical University(Nanjing Mater-nal and Child Health Hospital)from August 2021 to August 2023 were randomly selected as the study objects and ran-domly divided into two groups using a random number table method,with 35 cases in each group.The control group was treated with magnesium sulfate,while the observation group was treated with nifedipine tablets in combination with the control group.The treatment effects of two groups of patients were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically sig-nificant(P<0.05).There was no statistically significant difference in blood pressure levels between the two groups be-fore treatment(P>0.05).After treatment,the blood pressure levels in both groups improved,and the observation group showed a better improvement in blood pressure than the control group,and the difference was statistically significant(P<0.05).In the comparison of delivery methods,the observation group had a higher natural delivery rate than the con-trol group,and the difference was statistically significant(P<0.05).The difference in cesarean section rates between the two groups was not statistically significant(P>0.05).In the comparison of neonatal complications rates,the rate of fetal distress in the observation group was lower than that in the control group,and the difference was statistically sig-nificant(P<0.05).There was no statistically significant difference in the rates of neonatal asphyxia rate and mortality rate between the two groups(both P>0.05).Conclusion Nifedipine tablets combined with magnesium sulfate can im-prove the therapeutic results of hypertensive patients in pregnancy,can effectively reduce the patient's blood pressure level,and improve the rate of spontaneous delivery,with a high degree of safety.
Hypertension in pregnancyNifedipine tabletsMagnesium sulfatePrognosis
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NSTL
万方数据
维普
