Effect of Soft-channel Minimally Invasive Puncture and Drainage Com-bined with Sodium Aesculin in the Treatment of 33 Patients with Hyperten-sive Cerebral Hemorrhage
Objective To explore the clinical effect of soft-channel minimally invasive puncture and drainage com-bined with sodium aesculin in the treatment of hypertensive cerebral hemorrhage.Methods 66 patients with hyperten-sive intracerebral hemorrhage admitted to Fuzhou Changle District Hospital from January 2020 to September 2022 were conveniently selected as the study objects.They were divided into two groups according to random number table method,with 33 cases in each group.The control group received conventional treatment,and the observation group re-ceived soft-channel minimally invasive puncture and drainage combined with sodium escinate,and the relevant indi-cators of the two groups were compared.Results The therapeutic total effective rate of observation group was 96.97%,which was higher than that of control group(72.73%),and the difference was statistically significant(χ2=7.543,P<0.05).After intervention,the cerebral edema volume and nerve function in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).After intervention,the aquaporin-4 antibody(AQP4-Ab),human cell fibronectin(Cfn)and hypersensitive C-reactive protein(hs-CRP)in the observa-tion group were lower than those in the control group,and the difference was statistically significant(all P<0.05).Con-clusion In patients with hypertensive intracerebral hemorrhage,soft-channel minimally invasive puncture and drain-age combined with aesculin sodium intervention can significantly adjust AQP-Ab,Cfn,and hs-CRP of the patients,improve the neurological deficits of the patients,reduce the area of cerebral edema,reduce the amount of hematoma,and accelerate their consciousness.It has a certain promoting effect on the improvement of the overall treatment effi-ciency.