Analysis of the Effect of Amiodarone Combined with Irbesartan Therapy in the Treatment of Patients with Heart Failure Combined with Arrhyth-mia
Objective To investigate the effect of amiodarone combined with irbesartan application in the treatment of patients with heart failure combined with arrhythmia.Methods A total of 82 patients with heart failure combined with arrhythmia admitted to the Shandong Heze Sixth People's Hospital from January 2022 to June 2023 were conveniently selected as the study objects,and they were divided into observation group and control group by random table method,with 41 cases in each group.The control group was treated with amiodarone,and the observation group was treated with irbesartan on the basis of the control group.The cardiac function,6-Minute Walking Text test(6MWT),efficacy and occurrence of adverse reactions were compared between the two groups.Results Before treatment,there was no significant difference in cardiac function and 6MWT between the two groups(both P>0.05).After treatment,Stroke Volume(SV)and Left Ventricular Eject Fraction(LVEF)in the observation group were higher than those in the con-trol group,Left Ventricular Posterior Wall Thickness(LVWP)and Left Ventricular End Systolic Diameter(LVESD)were lower than those of control group,and the differences were statistically significant(all P<0.05).The 6MWT level of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The effective rate of observation group(97.56%)was higher than that of control group(80.49%),and the differ-ence was statistically significant(χ2=6.116,P=0.013).The incidence of adverse reactions in observation group(4.88%)was lower than that in control group(21.95%),and the difference was statistically significant(χ2=5.145,P= 0.023).Conclusion In the treatment of patients with heart failure and arrhythmia,amiodarone combined with irbesar-tan treatment can achieve significant efficacy,promote the improvement of the level of cardiac function of the patients,regulate the functions of the patients at the same time to reduce the incidence of adverse reactions of the patients.
NETL
NSTL
万方数据
维普
