Clinical Effect of Proximal Femoral Antirotation Intramedullary Nail Fixa-tion Combined with BMP-2 Bone Grafting in the Treatment of Elderly Femoral Intertrochanteric Comminuted Fracture
Objective To investigate the clinical effect of proximal femoral antirotation(PFNA)combined with bone morphogenetic protein-2(BMP-2)bone grafting in the treatment of comminuted femoral intertrochanteric fracture in elderly patients.Methods The clinical data of 80 elderly patients with intertrochanteric fractures of femur treated in the Department of Orthopedics of Putian First Hospital from August 2015 to March 2020 were retrospectively selected,and were divided into PFNA group(42 cases)and PFNA+BMP-2 bone grafting group(38 cases)according to different surgical methods.Operation time,intraoperative blood loss,weight-bearing walking time,fracture healing time and hip function scores of 2 weeks,3 months and 9 months after surgery were compared between the two groups.Results The fracture healing time and the time to start weight-bearing walking on the ground in the PFNA+BMP-2 implant group were(12.47±1.88)weeks and(12.64±1.95)weeks,respectively,which were significantly shorter than those in the PFNA group of(14.40±2.35)weeks and(13.36±2.37)weeks,and the differences were statistically significant(t= 4.028,4.048,both P<0.05).The hip function scores in the PFNA+BMP-2 implant group were(88.31±5.98)points and(91.38±4.66)points at 3,9 months after surgery,respectively,which were higher than the hip function scores in the PFNA group(82.86±7.17)points and(86.92±5.65)points,respectively,and the differences were statistically signifi-cant(t=3.670,3.828,both P<0.05).Conclusion PFNA combined with BMP-2 bone grafting can achieve good curative effect in the treatment of intertrochanteric comminuted fracture in elderly patients,and is especially suitable for the treatment of intertrochanteric fracture in elderly patients with osteoporosis,which is a safe and effective treatment method.
Proximal femoral antirotationBone graftingIntertrochanteric fracture of femurBone morphogenetic protein-2
NETL
NSTL
万方数据
维普
