摘要
目的 探讨对胰腺炎患者分别采用奥曲肽实施皮下注射治疗以及微量泵注治疗后获得的临床效果.方法 随机选取2020年2月—2022年4月漳平市医院收治的80例胰腺炎患者为研究对象,以随机数表法分为参照组和研究组,每组40例.参照组采用奥曲肽皮下注射治疗,研究组采用奥曲肽微量泵注治疗.对比两组治疗总有效率、系列时间指标(恢复进食时间、血淀粉酶恢复时间、腹痛消失时间、住院时间)、腹泻发生率.结果 研究组治疗总有效率高于参照组,差异有统计学意义(P<0.05).与参照组恢复进食时间(5.25±0.53)d、血淀粉酶恢复时间(6.26±2.11)d、腹痛消失时间(7.15±1.17)d以及住院时间(14.29±2.21)d比较,研究组胰腺炎患者恢复进食时间(3.53±0.26)d、血淀粉酶恢复时间(5.21±1.26)d、腹痛消失时间(4.11±1.06)d以及住院时间(9.21±2.26)d明显更短,差异有统计学意义(t=18.427、2.702、12.178、10.164,P均<0.05).两组腹泻发生率比较,差异无统计学意义(P>0.05).结论 同奥曲肽皮下注射治疗比较,选择奥曲肽微量泵注方法对胰腺炎患者展开治疗,可提升疗效,有效缩短恢复进食时间、血淀粉酶恢复时间、腹痛消失时间、住院时间,并且不会呈现出严重腹泻症状,可促进胰腺炎患者的良好预后.
Abstract
Objective To investigate the clinical effects of octreotide subcutaneous injection and micropump therapy in patients with pancreatitis.Methods A total of 80 patients with pancreatitis admitted to Zhangping City Hospital from February 2020 to April 2022 were randomly selected as the study objects,and were divided into the reference group and the study group by random number table method,with 40 cases in each group.The reference group was treated with octreotide subcutaneous injection,and the study group was treated with octreotide micropump.The total effective rate,serial time indexes(time to resume eating,time to recover blood amylase,time to disappear abdominal pain,time to stay in hospital)and incidence of diarrhea were compared between the two groups.Results The total effective rate of the study group was higher than that of the reference group,and the difference was statistically significant(P<0.05).Compared with in the control group the recovery time of eating(5.25±0.53)d,the recovery time of blood amylase(6.26±2.11)d,the disappearance time of abdominal pain(7.15±1.17)d and the hospitalization time(14.29±2.21)d in the control group,in the study group,the time to resume eating(3.53±0.26)d,the time to recover blood amylase(5.21±1.26)d,the time to disappear abdominal pain(4.11±1.06)d and the time to stay in hospital(9.21±2.26)d were signifi-cantly shorter,the difference was statistically significant(t=18.427,2.702,12.178,10.164,all P<0.05).There was no statistically significant difference in the incidence of diarrhea between the two groups(P>0.05).Conclusion Compared with octreotide subcutaneous injection,the selection of octreotide micropump method for the treatment of patients with pancreatitis can improve the curative effect,effectively shorten the time to resume eating,blood amylase recovery,ab-dominal pain disappearance and hospital stay,and will not present serious diarrhea symptoms,which can promote the good prognosis of patients with pancreatitis.
NETL
NSTL
维普
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