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黄连温胆汤加减治疗慢性肾衰竭的临床效果

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目的 研究黄连温胆汤加减治疗慢性肾衰竭的临床效果.方法 方便选取2021年1月—2023年9月淮安市洪泽区中医院收治的76例慢性肾衰竭患者为研究对象,以随机数表法分为对照组和观察组,各38例,分别采取常规治疗和联合黄连温胆汤加减治疗方式,分析两组中医症状积分、肾功能指标、治疗总有效率.结果 治疗后,观察组神疲乏力、食少纳呆、腰膝酸软、肢体麻木的中医症状积分分别为(2.42±0.41)分、(0.96±0.24)分、(1.02±0.27)分、(1.87±0.43)分,均低于对照组,差异有统计学意义(t=8.917、10.835、12.201、5.062,P均<0.05);治疗后,观察组24 h尿蛋白(0.88±0.14)mg/L、血肌酐(Serum Creatinine,SCr)(112.02±1.56)μmol/L、尿素氮(Blood Urea Nitrogen,BUN)水平(4.02±1.45)mmol/L,均优于对照组,差异有统计学意义(t=6.687、5.778、3.985,P均<0.05);观察组治疗总有效率(97.37%)高于对照组(78.95%),差异有统计学意义(P<0.05).结论 黄连温胆汤加减应用在慢性肾衰竭患者治疗过程中,取得显著治疗效果.
Clinical Effect of Huanglian Wendan Decoction on Chronic Renal Failure
Objective Analysis of the effect of chronic renal failure in the treatment of chronic renal failure.Methods A total of 76 patients with chronic renal failure admitted to Hongze District Hospital of Traditional Chinese Medicine of Huai'an City from January 2021 to September 2023 were conveniently selected as the study objects.They were ran-domly divided into control group and observation group by random number table method,38 cases in each group.Con-ventional treatment and combined treatment with Huanglian Wendan Decoction were adopted respectively,and TCM symptom score,renal function index and total treatment effective rate of the two groups.Result After treatment,the scores of traditional Chinese medicine symptoms of fatigue,eating less and being dull,waist and knee weakness and limb numbness in the observation group were(2.42±0.14)points,(0.96±0.24)points,(1.02±0.27)points and(1.87±0.43)points were lower than those of the control group,and the differences were statistically significant(t=8.917,10.835,12.201,5.062,all P<0.05).The levels of urinary protein,BUN and SCr at 24 h after treatment in the observa-tion group were(0.88±0.14)mg/L,(112.02±1.56)μmol/L and(4.02±1.45)mmol/L,respectively,which were better than those in the control group,the differences were statistically significant(t=6.687,5.778,3.985,all P<0.05);The total response rate(97.37%)was higher than the control group(78.95%),the difference was statistically significant(P<0.05).Conclusion The application of Huanglian Wendan Decoction in the treatment of patients with chronic renal fail-ure has achieved remarkable therapeutic effect.

Huanglian Wendan DecoctionChronic kidney failureClinical effect

陶杰、徐严、朱妍

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淮安市洪泽区中医院肾病科,江苏淮安 223100

黄连温胆汤 慢性肾衰竭 临床效果

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(6)
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