Effect of Liquid Nitrogen Freezing on Plantar Verruca and Immune Func-tion
Objective To analyze the effect of liquid nitrogen cryotherapy on immune function in patients with plantar verruca.Methods A total of 50 patients with plantar warts admitted to the Affiliated Hospital of Putian University from January 2020 to December 2022 were randomly selected as the study objects and divided into two groups by random number table method.25 patients in the observation group received liquid nitrogen cryotherapy and 25 patients in the control group received conventional treatment.The changes of CD3+,CD4+,CD4+/CD8+,visual analogue scale(VAS)/score,incidence of adverse reactions,interleukin-2(IL-2),interleukin-4(IL-4),interferon(INF-γ)levels before and after treatment were compared between the two groups.Results After treatment,the levels of CD3+,CD4+,CD4+/CD8+,VAS score,IL-2,IL-4 and INF-γ in observation group were better than ths those of control group,and the differ-ences were statistically significant(all P<0.05).The incidence of adverse reactions in observation group(4.0%)was lower than that in control group,and the difference was statistically significant(χ2=12.121,P<0.05).Conclusion com-pare with the conventional treatment,the patients with plantar verruca,liquid nitrogen cryotherapy can significantly improve immune function and the efficacy of disease treatment,reduce the degree of pain in the affected area and the incidence of adverse reactions,which is conducive to promoting physical rehabilitation after treatment.
NETL
NSTL
万方数据
维普
