乙型肝炎病毒与丙型肝炎病毒合并感染患者的生化免疫结果分析
Analysis of Biochemical Immune Results in Patients Co-infected with Hepatitis B Virus and Hepatitis C Virus
王秀和1
作者信息
- 1. 莆田涵江医院检验科,福建莆田 351100
- 折叠
摘要
目的 探讨乙型肝炎病毒与丙型肝炎病毒合并感染患者的生化免疫结果.方法 回顾性选取2018年10月—2022年10月莆田涵江医院确诊为乙型肝炎病毒和(或)丙型肝炎病毒感染的120例患者的临床资料,其中40例合并感染患者为观察组,40例乙型肝炎病毒感染患者为观察1组,40例丙型肝炎病毒感染患者为观察2组,均进行生化免疫指标检验,观察和记录3组的免疫结果.结果 观察组各项免疫学指标相比于观察1组、观察2组更高,差异有统计学意义(P均<0.05).观察组肝功能指标相比于观察1组更低,相比于观察2组更高,差异有统计学意义(P均<0.05).观察组凝血酶原时间相比于观察1组、观察2组更高;凝血酶原活动度相比于观察1组、观察2组更低,差异有统计学意义(P均<0.05).结论 乙型肝炎病毒与丙型肝炎病毒合并感染会降低患者的肝脏储备能力,增强炎症反应的发生,加重肝脏的损伤,同时凝血能力增强,可能会促使血栓的形成.
Abstract
Objective To investigate the biochemical and immune results of patients co-infected with hepatitis B virus and hepatitis C virus.Methods The clinical data of 120 patients diagnosed as infection of hepatitis B virus and(or)hepatitis C virus in Putian Hanjiang Hospital from October 2018 to October 2022 were retrospectively selected,of which 40 patients with combined infection were in the observation group,40 patients with hepatitis B virus infection were in the observation group 1,and 40 patients with hepatitis C virus infection were in the observation group 2.The biochemical immune indexes were tested,and the immune results of the 3 groups were observed and recorded.Results The immunological indexes in the observation group were higher than those in the observation group 1 and the obser-vation group 2,and the differences were statistically significant(all P<0.05).The liver function indexes of the observa-tion group were lower than those of the observation group 1,but higher than those of the observation group 2,and the differences were statistically significant(all P<0.05).The prothrombin time in observation group was higher than that in observation group 1 and observation group 2,prothrombin activity was lower than that in observation group 1 and observation group 2,and the differences were statistically significant(all P<0.05).Conclusion Hepatitis B virus and hepatitis C virus co-infected can reduce the liver reserve capacity of patients,enhance the occurrence of inflamma-tion,aggravate liver damage,and enhance the clotting ability,which may promote the formation of thrombus.
关键词
乙型肝炎病毒/丙型肝炎病毒/γ-干扰素/白介素-6/白介素-10Key words
Hepatitis B virus/Hepatitis C virus/γ-interferon/Interleukin-6/Interleukin-10引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据