Application of Ureteral Soft Scope in Patients with Kidney Stones and Its Influence on KIM-1,NGAL and Other Indexes
Objective To investigate the application of ureteral soft scope in patients with kidney stones and its effect on kidney injury molecule 1(KIM-1)and serum neutrophil gelatinase associated lipocalin(NGAL).Methods Clinical data of 200 patients with kidney stones treated in Gong'an Hospital Affiliated to Hubei University of Chinese Medi-cine from January 2022 to November 2023 were retrospectively selected,and they were divided into control group and study group according to different surgical methods,with 100 cases in each group.The control group received stan-dard percutaneous nephrolithotomy and the study group received ureteral soft lithotomy.The clinical effect of the two groups was compared.Results Compared with the preoperative level,the KIM-1 level in both groups was increased 1 d after surgery,and the differences were statistically significant(P<0.05).2 d after surgery,KIM-1 level in the study group was(86.21±24.31)ng/L,lower than that in the control group[(98.41±27.96)ng/L],the difference was statisti-cally significant(t=3.293,P=0.001).After operation,NGAL level in two groups of patients was significantly higher than before operation,the difference was statistically significant(P<0.05).The level of cystatin C(Cys-C)in the two groups was higher than that before surgery 1 and 2 d after surgery,and the level of Cys-C in the observation group was higher than that in the control group 3 d after surgery,the differences were statistically significant(P<0.05).Op-eration,hospital stay and hemoglobin decline in the study group were better than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in stone clearance between the two groups(P>0.05).Conclusion Flexible ureteral lithotomy for kidney stones can significantly shorten the opera-tion time,reduce the length of hospital stay,reduce the postoperative hemoglobin decline,and cause less trauma to pa-tients.
NETL
NSTL
万方数据
维普
