Analyzing the Safety and Efficacy of Esketamine Combined with Propofol for Painless Bronchoscopy Anesthesia
Objective To analyze the safety and effectiveness of esketamine combined with propofol for painless bron-choscopy anesthesia.Methods 100 patients for painless bronchoscopy admitted to Yantai Beihai Hospital from Octo-ber 2022 to April 2023 were selected simple randomly as study objects,and they were divided into a control group and an observation group of 50 patients each according to the method of random number table.The observation group was anesthetized with esketamine combined with propofol,and the control group was anesthetized with sufentanil com-bined with propofol.The mean arterial pressure,heart rate and oxygen saturation of two groups of patients at T0(be-fore anesthesia),T1(painless bronchoscopy tube placement),T2(bronchoscopy passing through the glottis),T3(bron-choscopy reaching the protuberance),T4(fiberoptic bronchoscopy removal),T5(patient awakening),and T6(end of ob-servation period),as well as anesthesia effects and adverse reaction occurrence were compared between the two groups.Results In stages T2,T3,and T4,the mean arterial pressure and heart rate in the obervation group were higher than those in the control group,and the differences were statistically significant(all P<0.05).In the T3 and T4 stages,the blood oxygen saturation,and the differences were statistically significant(both P<0.05).The incidence of coughing and time of awakening from anesthesia,the time of waking up from anesthesia of the patients in the observa-tion group were shorter than those of the control group,and the differences were statistically significant(all P<0.05).The total incidence of adverse reactions in the observation group was 4.00%,lower than the control group's 16.00%,and the difference was statistically significant(χ2=7.324,P<0.05).Conclusion The combined application of esket-amine and propofol can provide stable and effective anesthesia,reduce adverse reactions,and improve the safety and comfort of painless bronchoscopy.
NETL
NSTL
万方数据
维普
