阿加曲班在体外膜肺氧合中的应用
Application of Agatroban in Extracorporeal Membrane Oxygenation
章初寒 1卢安卫2
作者信息
- 1. 浙江中医药大学研究生院,浙江杭州 310035
- 2. 浙江树人学院树兰国际医学院,浙江杭州 310015
- 折叠
摘要
在体外膜肺氧合(Extracorporeal Membrane Oxygenation,ECMO)支持过程中,为了有效预防凝血并发症,选择合适的抗凝药物显得尤为关键.阿加曲班作为一种直接凝血酶抑制剂(Direct Thrombin Inhibitor,DTI),以其可控的抗凝监测、出色的抗凝效果和良好的安全性等特点,可能相较于传统的肝素(Unfraction-ated heparin,UFH)更为优越.本文综述了阿加曲班在ECMO中的应用,为抗凝治疗提供了更为个体化的选择,进一步丰富了ECMO抗凝策略.
Abstract
In the process of extracorporeal membrane oxygenation(ECMO)support,in order to effectively prevent co-agulation complications,it is particularly important to select appropriate anticoagulant drugs.Agatroban,as a direct thrombin inhibitor(DTI),may be superior to unfractionated heparin(UFH)because of its controllable anticoagulant monitoring,excellent anticoagulant effect and good safety.This article reviewed the application of agatroban in ECMO,which provided a more individualized choice for anticoagulant therapy and further enriched the anticoagulant strategy of ECMO.
关键词
阿加曲班/体外膜肺氧合/抗凝Key words
Agatroban/Extracorporeal membrane oxygenation/Anticoagulation引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据