丙泊酚与咪达唑仑在急性脑出血手术患者中的应用效果分析
Effect of Propofol and Midazolam on Patients undergoing Acute Cerebral Hemorrhage Surgery
曾芳鑫 1耿坤 1沙丁1
作者信息
摘要
目的 分析急性脑出血手术患者采用丙泊酚与咪达唑仑进行麻醉的应用效果.方法 单纯随机选取于2022年1-12月冠县人民医院收治的80例急性脑出血手术患者作为研究对象,按照抽签形式分为对照组和观察组,各40例.对照组手术麻醉用药为咪达唑仑,观察组手术麻醉用药为丙泊酚,比较两组生命体征、麻醉指标、不良反应发生率.结果 观察组较对照组的生命体征指标稳定,差异有统计学意义(P均<0.05);观察组的麻醉指标优于对照组,差异有统计学意义(P均<0.05);观察组不良反应发生率(5.00%)显著低于对照组(20.00%),差异有统计学意义(χ2=4.114,P<0.05).结论 急性脑出血患者行手术期间,用丙泊酚做手术麻醉用药,可维护其生命体征稳定,且手术麻醉具有良好的时效性及较高的麻醉安全性.
Abstract
Objective To analyze the effect of using propofol and midazolam for anesthesia in patients undergoing acute cerebral hemorrhage surgery.Methods A total of 80 patients with acute cerebral hemorrhage surgery admitted to Guanxian People's Hospital from January to December 2022 were randomly selected as the study objects,and were divided into control group and observation group according to the form of lottery,with 40 cases in each group.Midazolam was used as anesthetic drug in the control group,and propofol was used as anesthetic drug in the observa-tion group.Vital signs,anesthetic indexes and incidence of adverse reactions were compared between the two groups.Results The vital signs of the observation group were more stable compared with the control group,and the differ-ences were statistically significant(all P<0.05).The anesthesia indexes of the observation group were better than those of the control group,and the differences were statistically significant(all P<0.05).The incidence of adverse re-actions in observation group(5.00%)was significantly lower than that in control group(20.00%),and the difference was statistically significant(χ2=4.114,P<0.05).Conclusion The use of propofol for surgical anesthesia in patients with acute cerebral hemorrhage during operation can maintain the stability of their vital signs,and surgical anesthe-sia has good timeliness and high anesthesia safety.
关键词
丙泊酚/咪达唑仑/急性脑出血/手术麻醉/应用效果Key words
Propofol/Midazolam/Acute cerebral hemorrhage/Surgical anesthesia/Application effect引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据