Clinical Effect and Safety of Emergency Thrombolysis and Teneplase Com-bined with Guanxinning in the Treatment of Senile Acute Myocardial In-farction
Objective To analyze the clinical effect and safety of emergency thrombolysis and teneplase combined with Guanxinning in the treatment of senile acute myocardial infarction.Methods A total of 80 elderly patients with acute myocardial infarction received percutaneous coronary intervention(PCI)in Xinyi Hospital of Traditional Chinese Medicine from October 2020 to June 2023 were randomly selected as the research objects.They were divided into con-trol group and observation group according to odd-even number method,singular number was divided into control group(40 cases,conventional thrombolytic therapy),and even number was divided into observation group(40 cases,on the basis of control group plus teneplase combined with Guanxinning treatment).The clinical therapeutic effect,cardiac function indexes and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 95.00%,which was higher than that of the control group 77.50%,the difference was sta-tistically significant(χ2=5.165,P<0.05).After treatment,the left ventricular end-systolic diameter in the observation group was(42.32±4.65)mm,which was lower than that in the control group[(45.46±4.73)mm],the left ventricular ejection fraction of the observation group was(57.24±8.03)%,which was higher than control group[(50.31±7.97)%],the differences were statistically significant(t=2.994,3.874,both P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Teneplase combined with Guanxinning in elderly patients with acute myocardial infarction on the basis of conventional thrombolytic therapy can further improve the clinical effect,promote patients'heart function,and do not increase the risk of medication,with high safety.
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万方数据
维普
