首页|对治疗脑卒中后癫痫患者行丙戊酸钠联合左乙拉西坦的CRP、总有效率效果分析

对治疗脑卒中后癫痫患者行丙戊酸钠联合左乙拉西坦的CRP、总有效率效果分析

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目的 分析丙戊酸钠联合左乙拉西坦在治疗脑卒中后癫痫患者中的疗效.方法 随机选取2020年1月—2023年1月东海县人民医院收治的80例脑卒中后癫痫患者为研究对象.以奇偶法分为两组,普通组(n=40)接受单丙戊酸钠治疗;观察组(n=40)给予丙戊酸钠联合左乙拉西坦治疗.比较两组康复总有效率、炎症因子指标、神经功能评分以及不良反应发生情况.结果 治疗后,观察组康复总有效率为92.50%,高于普通组的75.00%,差异有统计学意义(χ2=4.501,P=0.034);观察组炎症因子指标和神经功能评分均优于普通组,差异有统计学意义(P均<0.05).两组不良反应总发生率比较,差异无统计学意义(P>0.05).结论 丙戊酸钠联合左乙拉西坦治疗脑卒中后癫痫的效果确切,不良反应少.
Total Effective Rate and CRP of Sodium Valproate Combined with Leveti-racetam in Patients with Epilepsy after Stroke
Objective To analyze the efficacy of sodium valproate combined with levetiracetam in the treatment of epilepsy after stroke.Methods A total of 80 patients with post-stroke epilepsy admitted to Donghai County People's Hospital from January 2020 to January 2023 were randomly selected as the study objects.They were divided into two groups by odd-even method.The normal group(n=40)received monovalproate,and the observation group(n=40)was given sodium valproate combined with levetiracetam.The total effective rate of rehabilitation,inflammatory fac-tor index,neurological function score and the occurrence of adverse reactions were compared between the two groups.Results After treatment,the total effective rate of the observation group was 92.50%,higher than 75.00%in the normal group,and the difference was statistically significant(χ2=4.501,P=0.034).The inflammatory factor indexes and neurological function scores of the observation group were better than those of the normal group,and the differ-ences were statistically significant(both P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The efficacy of sodium valproate combined with levetiracetam in the treatment of epilepsy after stroke is precise and the adverse reactions are few.

StrokeEpilepsySodium valproateLevetiracetamEffect

庄国芹、蒋春玲

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东海县人民医院神经内科,江苏连云港 222300

脑卒中 癫痫 丙戊酸钠 左乙拉西坦 效果

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(9)