中外医疗2024,Vol.43Issue(9) :112-115.DOI:10.16662/j.cnki.1674-0742.2024.09.112

丁苯酞氯化钠联合己酮可可碱对急性脑梗死患者NIHSS、ADL评分的影响

Effects of Sodium Butylphthalein Chloride Combined with Pentoxifylline on NIHSS and ADL Scores in Patients with Acute Cerebral Infarction

寿利军 赵晗孜 胡从庆
中外医疗2024,Vol.43Issue(9) :112-115.DOI:10.16662/j.cnki.1674-0742.2024.09.112

丁苯酞氯化钠联合己酮可可碱对急性脑梗死患者NIHSS、ADL评分的影响

Effects of Sodium Butylphthalein Chloride Combined with Pentoxifylline on NIHSS and ADL Scores in Patients with Acute Cerebral Infarction

寿利军 1赵晗孜 1胡从庆1
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作者信息

  • 1. 宿迁市沭阳仁慈医院神经内科,江苏宿迁 223600
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摘要

目的 探究急性脑梗死患者应用丁苯酞氯化钠联合已酮可可碱治疗的作用.方法 便利选取2022年1月—2023年10月宿迁市沭阳仁慈医院收治的96例急性脑梗死患者为研究对象.采用盲摸双色球法分为研究组和参照组,各48例.参照组治疗药物为己酮可可碱,研究组加用丁苯酞氯化钠治疗.比较两组的相关临床指标.结果 研究组临床疗效(97.92%)高于参照组(85.42%),差异有统计学意义(χ2=4.909,P<0.05).干预后,两组神经功能水平评分低于干预前,且研究组低于参照组,差异有统计学意义(P<0.05).研究组日常生活能力评分高于参照组,差异有统计学意义(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 丁苯酞氯化钠联合己酮可可碱治疗能够提高患者的治疗效果,改善神经功能水平及日常生活能力,且安全性较高.

Abstract

Objective To investigate the effect of sodium butylphthalein chloride combined with pentoxifylline in the treatment of acute cerebral infarction.Methods A total of 96 patients with acute cerebral infarction who visited Shuy-ang Renci Hospital,Suqian City from January 2022 to October 2023 were conveniently selected as the study objects.All patients were divided into study group and reference group with 48 cases in each group according to the method of two-color ball.The reference group was treated with pentoxifylline,and the study group was treated with butylphtha-lein sodium chloride.The relevant clinical indicators of the two groups were compared.Results The clinical efficacy level of the study group was 97.92%,higher than 85.42%of the reference group,and the difference was statistically sig-nificant(χ2=4.909,P<0.05).The score of neurological function of the two group after intervention were lower than those before intervention,and that in the study group was lower than that in the reference group,and the differences were statistically significant(P<0.05).The daily living ability score of the study group was higher than that of the refer-ence group,and the difference was statistically significant(P<0.05).There was no significant difference in the inci-dence of adverse reactions was compared between the two groups(P>0.05).Conclusion The treatment of butylphtha-lein sodium chloride combined with pentoxifylline can improve the therapeutic effect of patients,improve the level of nerve function and daily living ability,and has high safety.

关键词

丁苯酞氯化钠/己酮可可碱/急性脑梗死/治疗效果/神经功能/日常生活能力/不良反应

Key words

Butylphthalein sodium chloride/Pentoxifylline/Acute cerebral infarction/Therapeutic effect/Nerve function/Ability of daily living/Adverse reaction

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出版年

2024
中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
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