Value of Different Blood Purification Methods in the Control of Acute Kid-ney Injury
Objective To analyze the time and method of blood purification in treating acute kidney injury.Methods A total of 60 patients with acute kidney injury admitted to Jiangsu Rudong Yangkou Hospital from January 2020 to January 2023 were randomly selected as the study objects and were divided into the the observation group and the con-trol group by random number table method,with 30 cases in each group.All patients were treated with blood purifica-tion.The observation group received continuous renal replacement therapy,and the control group received intermittent renal replacement therapy.The clinical efficacy,renal function,inflammatory factor levels and clinical indexes of the two groups were compared.Results The clinical efficacy of the observation group was 93.33%,higher than 73.33%of the control group,the difference was statistically significant(χ2=4.320,P<0.05).After treatment,the leves of serum creatinine,urea nitrogen and aspartate aminotransferase in the observation group were lower than those of the control group,glomerular filtration rate was higher than that of the control group,and the differences were statistically signifi-cant(all P<0.05).After treatment,the leves of C-reactive protein,procalcitonin,interleukin-6 and tumor necrosis fac-tor-α in both groups were lower than those before teatment,and those of the observation group were lower than those of the control group,and the differences were statistically significant(all P<0.05).The scores of acute physiology and chronic health status scoring system in observation group was lower than that of the control group,and the time of stay in intensive care unit was shorter than that of the control group,and the differences were statistically significant(both P<0.05).Conclusion Providing continuous renal replacement therapy after a clear diagnosis of acute renal injury can improve the level of renal function and inflammatory factors,and shorten the time of hospitalization in intensive care unit.
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