腹腔镜手术与开腹手术治疗胃肠道穿孔的疗效研究
Effect of Laparoscopic and Open Surgery on Gastrointestinal Perforation
吴海彪 1何亦工 1何龙贵1
作者信息
- 1. 福建省武夷山市立医院普外科,福建武夷山 354300
- 折叠
摘要
目的 分析腹腔镜手术治疗胃肠道穿孔的效果.方法 方便选取2021年5月—2023年12月武夷山市立医院收治的98例胃肠道穿孔患者,根据密闭信封法分为对照组(n=49)、研究组(n=49).对照组行开腹手术治疗,研究组实施腹腔镜手术.对比两组手术指标,术前及术后1 d超敏C反应蛋白(High-sensitivity C-reactive Protein,hs-CRP)、肿瘤坏死因子-α(Tumor Necrosis Factor Alpha,TNF-α)及白细胞介素6(Interleukin-6,IL-6)水平,对比肠粘连、腹腔感染、切口感染发生率,对比术前及术后1个月生活质量简表(World Health Organization Quality of Life-100,WHOQOL-100)评分.结果 研究组各项手术指标均优于对照组,差异有统计学意义(P均<0.001);术后1 d,研究组hs-CRP、TNF-α、IL-6水平均低于对照组,差异有统计学意义(P均<0.001);研究组并发症发生率为2.04%,低于对照组的14.29%,差异有统计学意义(χ2=4.900,P=0.027);术后1个月,研究组WHOQOL-100评分高于对照组,差异有统计学意义(P<0.05).结论 腹腔镜手术治疗胃肠道穿孔效果较优,能够改善炎症指标水平,降低并发症风险,促进术后康复,提高患者生活质量.
Abstract
Objective To analyze the effect of laparoscopic surgery on gastrointestinal perforation.Methods A total of 98 patients with gastrointestinal perforation admitted to Wuyishan Municipal Hospital from May 2021 to December 2023 were conveniently selected and divided into control group(n=49)and study group(n=49)according to sealed envelope method.The control group underwent open surgery,and the study group underwent laparoscopic surgery.The surgical indicators and levels of high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor alpha(TNF-α)and interleukin-6(IL-6)in the two groups before and one day after surgery were compared between two groups.The incidence of intestinal adhesion,abdominal infection and incision infection was compared.The World Health Or-ganization Quality of Life-100(WHOQOL-100)scores were compared before and one month after surgery.Results All surgical indicators in the study group were better than those in the control group,the differences were statisti-cally significant(all P<0.001).The levels of hs-CRP,TNF-α and IL-6 in the study group were lower than those in the control group one day after surgery,the differences were statistically significant(all P<0.001).The complication rate of the study group was 2.04%,which was lower than that of the control group 14.29%,the difference was statis-tically significant(χ2=4.900,P=0.027).One month after operation,the WHOQOL-100 score of the study group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion Laparoscopic surgery is effective in the treatment of gastrointestinal perforation,which can improve the level of inflammation indi-cators,reduce the risk of complications,promote postoperative rehabilitation and improve the quality of life of pa-tients.
关键词
腹腔镜/开腹手术/胃肠道穿孔/机体损伤/炎症指标/生活质量Key words
Laparoscopy/Open surgery/Gastrointestinal perforation/Body injury/Indicators of inflammation/Quality of life引用本文复制引用
出版年
2024
NETL
NSTL
万方数据