Clinical Study of Azithromycin Combined with Salbutamol and Budesonide Aerosol Inhalation in the Treatment of Pediatric Mycoplasma Infantile Asthma
Objective To investigate the clinical effect of the combination of aerosol inhalation of salbutamol and budesonide with oral azithromycin during the treatment of pediatric asthma induced by mycoplasma infection.Methods A total of 120 children with asthma caused by mycoplasma infection admitted to Minqing County General Hospital from January 2018 to January 2021 were randomly selected as the study objects.They were divided into two groups,with 60 cases in each group by random number table method.The control group was treated with oral azithromycin+aerosol in-halation budesonide fog,while the study group was treated with aerosol inhalation of salbutamol and budesonide com-bined with oral azithromycin.The situation after treatment between the two groups were compared.Results The total ef-fective rate of the study group was 98.33%,which was higher than 88.33%in the control group,and the difference was statistically significant(χ2=4.821,P<0.05).The time for disappearance of lung moist rales,dyspnea,and cough in the study group were shorter than those of the control group,and the differences were statistically significant(all P<0.05).There was no statistically significant difference in total incidence of adverse reactions between the two groups of pa-tients(P>0.05).After treatment,the quality of life of the patients improved in two groups,and the study group had higher score than the control group,and the differences were statistically significant(both P<0.05).Conclusion During the treatment of mycoplasma infected children with asthma,on the basis of azithromycin treatment,the application of atomized inhalation combined with salbutamol and budesonide is conducive to improving the comprehensive treatment level of children.