首页|连续性肾脏替代治疗与普通血液透析治疗慢性肾病合并心力衰竭患者的临床效果比较

连续性肾脏替代治疗与普通血液透析治疗慢性肾病合并心力衰竭患者的临床效果比较

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目的 比较两种不同的方法治疗慢性肾病(Chronic Kidney Disease,CKD)合并心力衰竭(Heart Failure,HF)患者的临床效果.方法 方便选取2020年1月—2023年1月武威市凉州医院重症医学科收治的91例CKD合并HF患者为研究对象,以随机数表法分为对照组(n=45,普通血液透析治疗)和观察组[n=46,连续性肾脏替代治疗(Continuous Renal Replacement Therapy,CRRT)]治疗,对比两组临床疗效、生命体征、心功能指标及肾功能指标.结果 观察组临床总有效率为 97.83%,高于对照组的 80.00%,差异有统计学意义(x2=5.680,P<0.05).治疗后,两组患者心率、呼吸频率、平均动脉压及血清尿素氮、肌酐、半胱氨酸蛋白酶抑制剂均下降,观察组优于对照组,差异有统计学意义(P均<0.05).治疗后,两组左心室射血分数、6 min步行距离较治疗前上升,左心室舒张末期内径及左心室收缩末期内径下降,且观察组各项指标优于对照组,差异有统计学意义(P均<0.05).结论 CRRT治疗CKD合并HF临床疗效更优,可维持患者生命体征稳定状态,有效改善患者心功能及肾功能状态,利于疾病转归.
Comparison of Clinical Effects of Continuous Renal Replacement Therapy and Common Hemodialysis with Chronic Kidney Disease Complicated with Heart Failure
Objective To compare the clinical effects of two different methods in the treatment of chronic kidney dis-ease(CKD)complicated with heart failure(HF).Methods A total of ninety-one patients with CKD combined with HF treated in the Department of Critical Care Medicine,Wuwei Liangzhou Hospital from January 2020 to January 2023 were conveniently selected as the study objects.They were divided into control group(n=45,common hemodi-alysis treatment)and observation group[n=46,continuous renal replacement therapy(CRRT)]using random number table method.The clinical efficacy,vital signs,cardiac and renal function indicators of the two groups were com-pared.Results The total clinical effective rate of the observation group was 97.83%,which was higher than the control group's 80.00%,and the difference was statistically significant(x2=5.680,P<0.05).After treatment,the heart rate,re-spiratory rate,mean arterial pressure,blood urea nitrogen,creatinine,and cystatin C decreased in two groups of pa-tients,the observation group was better than those of the control group,and the differences were statistically signifi-cant(all P<0.05).After treatment,the left ventricular ejection fraction and 6-minute walking distance of the two groups increased compared to before treatment,while the left ventricular end diastolic diameter and left ventricular end systolic diameter decreased,and those indexes of the observation group had better than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion CRRT has better clinical efficacy in the treatment of CKD combined with HF,can maintain the stable state of patients'vital signs,effectively improve the car-diac function and renal function of patients,and is beneficial to the outcome of the disease.

Chronic kidney diseaseHeart failureContinuous renal replacement therapyHemodialysis

王淑萍、李凌霄

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武威市凉州医院重症医学科,甘肃武威 733000

慢性肾病 心力衰竭 连续性肾脏替代治疗 血液透析

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(12)