首页|依诺肝素钠联合双下肢气压治疗对股骨颈骨折患者术后凝血功能及静脉血栓形成的影响分析

依诺肝素钠联合双下肢气压治疗对股骨颈骨折患者术后凝血功能及静脉血栓形成的影响分析

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目的 分析依诺肝素钠联合双下肢气压治疗在股骨颈骨折患者术后治疗中的应用对患者凝血功能、静脉血栓形成的影响.方法 方便选取2021年1月—2023年10月盱眙县人民医院收治的92例行手术治疗的股骨颈骨折患者为研究对象,用随机数表法分为对照组和观察组,各46例.对照组术中注射依诺肝素钠治疗,观察组术中注射依诺肝素钠联合双下肢气压治疗.比较两组凝血功能、不良反应发生率、患侧小腿周径、下肢深静脉血栓发生情况.结果 治疗前两组凝血功能对比,差异无统计学意义(P>0.05);治疗后观察组凝血功能优于对照组,差异有统计学意义(P<0.05).观察组不良反应总发生率(2.17%)低于对照组(15.22%),差异有统计学意义(x2=4.929,P=0.026).治疗前两组患者患侧小腿周径比较,差异无统计学意义(P>0.05),治疗后观察组的患侧小腿周径小于对照组,差异有统计学意义(P<0.05).观察组的总血栓发生率(2.17%)低于对照组(13.04%),差异有统计学意义(x2=3.866,P=0.049).结论 依诺肝素钠与双下肢气压联合运用到股骨颈骨折患者治疗中,能有效降低患者凝血功能异常的情况,改善患者下肢静脉血流速度,降低静脉血栓形成的风险,具有较高治疗价值.
Effect of Enoxaparin Sodium Combined with Pressure Treatment of Both Lower Limbs on Coagulation Function and Venous Thrombosis in Patients with Femoral Neck Fracture after Operation
Objective To analyze the effects of enoxaparin sodium combined with lower extremity pressure therapy on coagulation function and venous thrombosis in patients with femoral neck fracture.Methods A total of 92 patients with femoral neck fracture who underwent surgical treatment in Xuyi County People's Hospital from January 2021 to October 2023 were conveniently selected as the study objects,and were divided into control group and observation group by random table method,with 46 cases in each group.The control group was treated with intraoperative injec-tion of enoxaparin sodium,and the observation group was treated with intraoperative injection of enoxaparin sodium combined with pressure treatment of both lower limbs.The coagulation function,the incidence of adverse reactions,the circumference of the affected leg and the occurrence of deep venous thrombosis were compared between the two groups.Results There was no significant difference in coagulation function between the two groups before treatment(P>0.05);after treatment,the coagulation function of observation group was better than that of control group,and the dif-ference was statistically significant(P<0.05).The total incidence of adverse reactions in observation group(2.17%)was lower than that in control group(15.22%),and the difference was statistically significant(x2=4.929,P=0.026).Be-fore treatment,there was no statistical significance in the circumference of the affected leg between the two groups(P>0.05);after treatment,the circumference of the affected leg in the observation group was smaller than that in the control group,the difference was statistically significant(P<0.05).The total thrombus incidence in the observation group(2.17%)was lower than that in the control group(13.04%),and the difference was statistically significant(x2=3.866,P=0.049).Conclusion The combination of enoxaparin sodium and lower limb pressure in the treatment of femoral neck fracture can effectively reduce the abnormal coagulation function of patients,improve the venous blood flow velocity of patients,and reduce the risk of venous thrombosis,which has high therapeutic value.

Enoxaparin sodiumPressure treatment of both lower limbsFemoral neck fractureCoagulation functionVenous thrombosis

刘绩、施军

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盱眙县人民医院药剂科,江苏盱眙 211700

盱眙县人民医院骨科,江苏盱眙 211700

依诺肝素钠 双下肢气压治疗 股骨颈骨折 凝血功能 静脉血栓形成

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(12)