首页|睑板腺按摩联合玻璃酸钠滴眼液在干眼症患者中的应用研究

睑板腺按摩联合玻璃酸钠滴眼液在干眼症患者中的应用研究

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目的 探讨睑板腺按摩联合玻璃酸钠滴眼液在干眼症患者中的应用价值.方法 方便选取2023年1-12月钟山人民医院门诊收治的72例干眼症患者为研究对象,以信封法随机分为研究组与参照组,各36例.参照组采用睑板腺按摩,研究组采用玻璃酸钠滴眼液联合睑板腺按摩,治疗周期均为4周.比较治疗前后两组眼表疾病指数(Ocular Surface Disease Index,OSDI)、泪膜功能指标、不良反应发生率.结果 治疗后,研究组OSDI量表各部分评分、总分均低于参照组,差异有统计学意义(P均<0.05).研究组角膜荧光素染色评分低于参照组,泪液分泌实验及泪膜破裂时间优于参照组,差异有统计学意义(P均<0.05).研究组不良反应发生率低于参照组(5.56%vs 11.11%),但差异无统计学意义(P>0.05).结论 予以干眼症患者睑板腺按摩联合玻璃酸钠滴眼液治疗可有效减轻其干眼程度,对泪膜功能的提升有积极意义,且联合用药未增加不良反应发生风险.
Study on the Application of Blepharoplasty Massage Combined with So-dium Hyaluronate Eye Drops in Patients with Dry Eye Disease
Objective To explore the application value of blepharoplasty massage combined with sodium hyaluronate eye drops in patients with dry eye disease.Methods A total of 72 patients with dry eye treated in outpatient depart-ment of Zhongshan People's Hospital from January to December 2023 were conveniently selected as the study objects and divided into study group and reference group by envelope method,with 36 cases in each group.The reference group were treated with meibomian gland massage,and the study group was treated with sodium hyaluronate eye drops combined with meibomian gland massage,and the treatment cycle was 4 weeks.Ocular Surface Disease Index(OSDI),tear film function index,and the incidence of adverse reactions were compared between the two groups before and after treatment.Results After treatment,the scores of all parts of OSDI scale,total score in the study group were lower than those in the reference group,and the differences were statistically significant(both P<0.05).The score of corneal fluorescein staining in the study group was lower than that in the reference group,and the duration of tear se-cretion test and tear film rupture were better longer than that in the reference group,and the differences were statisti-cally significant(all P<0.05).The incidence of adverse reactions in the study group was lower than that in the refer-ence group(5.56%vs 11.11%),but the difference was not statistically significant(P>0.05).Conclusion Blepharo-plasty massage combined with sodium hyaluronate eye drops in patients with dry eye can effectively reduce the degree of dry eye,which has a positive significance on the enhancement of tear film function,and the combination of drugs does not increase the adverse reactions risk.

BlepharoplastyDry eyeTear film functionSodium hyaluronate eye dropsAdverse effects

洪宏、李忠莉、吴瑕

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六盘水市钟山人民医院眼科,贵州六盘水 553000

睑板腺按摩 干眼症 泪膜功能 玻璃酸钠滴眼液 不良反应

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(12)