Effect of Esomeprazole Magnesium Enteric-coated Tablets Combined with Cisapride in the Treatment of Emergency Reflux Esophagitis
Objective To analyze the effect of esomeprazole magnesium enteric-coated tablets combined with Cis-apride in the treatment of emergency reflux esophagitis.Methods A total of 50 patients with emergency reflux esopha-gitis admitted to Ningyang County Hospital of Traditional Chinese Medicine from January to December 2022 were ran-domly selected as the study objects and randomly divided into study group and control group by drawing lots,with 25 patients in each group.The control group was treated with esomeprazole magnesium enteric-coated tablets,and the study group was treated with esomeprazole magnesium enteric-coated tablets combined with Cisapride.The total effec-tive rate,endoscopic grading score,serum inflammatory factor level and clinical symptom score of the two groups were compared.Results The total effective rate of treatment in the study group(96.00%)was higher than that in the control group(80.00%),the difference was statistically significant(x2=4.020,P<0.05).The endoscopic grading score,the level of serum interleukin-23 and interleukin-17,the symptom score of heartburn,acidf reflux and chest pain of the study group were lower than those of the control group,the differences were statistically significant(all P<0.05).Con-clusion Esomeprazole magnesium enteric-coated tablet combined with Cisapride has a significant effect on emergency reflux esophagitis,which can improve the endoscopy results,serum inflammatory factor levels and clinical symptoms of patients.
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