Evaluation of Clinical Prognosis of Elderly Patients with Unstable Angina Pectoris Caused by Coronary Heart Disease Treated with Metoprolol
Objective To explore the effect of metoprolol in elderly patients with unstable angina pectoris of coronary atherosclerotic heart disease(hereinafter referred to as coronary heart disease).Methods A total of 88 elderly patients with unstable angina pectoris of coronary heart disease admitted to Hekou District Hospital of Traditional Chinese Medicine of Dongying City from October 2021 to June 2023 were conveniently selected as the research objects,and they were divided into two groups according to the principle of random lottery,with 44 cases in each group.The con-trol group was treated with conventional therapy,and the drug isosorbide dinitrate and aspirin enteric-coated tablets were selected.The observation group was treated with metoprolol on the basis of the control group.The cardiac func-tion indexes and treatment effects of the two groups were compared.Results After treatment,the left ventricular ejec-tion fraction and cardiac output in the observation group were higher than those in the control group,and the left ven-tricular end-diastolic diameter was lower than those in the control group,the differences were statistically significant(all P<0.05).After treatment,nitric oxide in the observation group was higher than that in the control group,endothe-lin-1,creatine kinase and serum brain natriuretic peptide were lower than those in the control group,and the differ-ences were statistically significant(all P<0.05).The total effective rate of treatment in the observation group was 95.45%,which was higher than 81.82% in the control group,and the difference was statistically significant(χ2=4.062,P<0.05).Conclusion The use of metoprolol in the treatment of elderly patients with unstable angina pectoris with coro-nary heart disease has significant advantages in improving cardiac function,and this method has high clinical efficacy.
Coronary heart diseaseUnstable angina pectorisElderly patientsMetoprololCardiac function indexClinical effectSerum index
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