首页|孟鲁司特钠治疗小儿喘息性支气管炎缓解患儿临床症状的效果分析

孟鲁司特钠治疗小儿喘息性支气管炎缓解患儿临床症状的效果分析

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目的 分析孟鲁司特钠用于小儿喘息性支气管炎患儿治疗期间对患儿症状消失时间、实验室指标与并发症方面所产生的相关影响.方法 单纯随机选取2022年3月—2023年3月北京市顺义区医院治疗的80例小儿喘息性支气管炎患儿为研究对象,将患儿按照临床治疗方案的差异分为观察组与对照组,每组40例,对照组实施布地奈德治疗,观察组则实施孟鲁司特钠治疗,比较两组患儿症状消失时间、实验室指标与并发症发生率.结果 观察组患儿咳嗽缓解时间(5.91±1.16)d、湿啰音消失时间(6.26±1.03)d、哮鸣音消失时间(5.46±0.86)d与喘息消失时间(4.53±0.87)d明显优于对照组,差异有统计学意义(t=3.679、7.679、7.375、8.426,P均<0.05).治疗后,观察组患儿相关实验室指标优于对照组,差异有统计学意义(P<0.05).观察组并发症发生率明显低于对照组,差异有统计学意义(P<0.05).结论 孟鲁司特钠在小儿喘息性支气管炎患儿治疗期间能够有效提高患儿的临床治疗效果,也能够缩短临床症状消退时间,且能够有效降低患儿治疗后并发症发生率,促使患儿获得较快的康复.
Effect of Montelukast Sodium on Relieving Clinical Symptoms of Children with Asthmatic Bronchitis
Objective To analyze the effects of montelukast sodium on symptom resolution time,laboratory indicators and complications of children with asthmatic bronchitis during treatment.Methods A total of 80 children with asth-matic bronchitis treated in Beijing Shunyi District Hospital from March 2022 to March 2023 were randomly selected as the study objects,and the children were divided into observation group and control group according to the differ-ences in clinical treatment plans,with 40 cases in each group.The control group was treated with budesonide,while the observation group was treated with montelukast sodium.The time of symptom resolution,laboratory indexes and complication rate were compared between the two groups.Results The duration of cough relief[(5.91±1.16)d],the du-ration of wet rale disappearance[(6.26±1.03)d],the duration of wheezing[(5.46±0.86)d]and the duration of wheezing disappearance[(4.53±0.87)d]in the observation group were significantly better than those in the control group,and the differences were statistically significant(t=3.679,7.679,7.375,8.426,all P<0.05).After treatment,the relevant laboratory indexes in the observation group was better than that in the control group,and the difference was statisti-cally significant(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion During the treatment of children with asthmatic bronchitis,montelukast sodium can effectively improve the clinical treatment effect of children,shorten the time for clinical symptoms to resolve,and effectively reduce the complications of children after treatment,thus pro-moting the rapid recovery of children.

Montelukast sodiumAsthmatic bronchitis in childrenClinical symptomsLaboratory indicatorsComplication

高程凤、孙蕊、郑新

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北京市顺义区医院儿科,北京 101300

孟鲁司特钠 小儿喘息性支气管炎 临床症状 实验室指标 并发症

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(14)
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