Effect of Rosallistat on Microinflammatory Status and Anemia Indexes in Patients with Renal Anemia
Objective To analyze the effects of erythropoietin therapy and rosallistat therapy on microinflammatory sta-tus and anemia indexes in patients with renal anemia.Methods The clinical data of 70 patients with renal anemia treated in Shanghai Tianyou Hospital from January 2020 to January 2024 were retrospectively selected and grouped according to different treatment regimens.The control group(35 cases)was treated with erythropoietin,and the study group(35 cases)was treated with rosallistat.Anemia indexes,microinflammation and inflammation indexes,iron me-tabolism indexes,and incidence of adverse reactions were compared between the two groups before and after treat-ment.Results After treatment,the erythrocyte count,hematocrit and hemoglobin levels in the study group were higher than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the aver-age levels of C-reactive protein,interleukin-6 and calcitonin in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the transferrin saturation was(35.81±3.62)% and ferritin level was(292.32±38.65)µg/L,which in the study group were higher than those in the control group,and the differences were statistically significant(t=11.166,8.322,both P<0.05).The incidence of ad-verse reactions in the study group was similar to that in the control group,but the difference was not statistically sig-nificant(P>0.05).Conclusion Roxallistat treatment for renal anemia patients has a significant effect,can alleviate ane-mia symptoms,reduce micro-inflammation,promote iron metabolism level recovery,with high safety.
Renal anemiaAnemia indexRoxallistatMicroinflammatory state
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