Effect of Hormone Replacement Therapy on Improving Symptoms and Quality of Life in Women with Perimenopausal Syndrome
Objective To investigate the effectiveness of hormone replacement therapy in relieving symptoms associ-ated with perimenopausal syndrome in women and its impact on quality of life.Methods Clinical data of 120 pa-tients with perimenopausal syndrome admitted to Xinzhou Central Hospital from January 2022 to December 2023 were retrospectively selected.According to different treatment methods,they were divided into routine group(n=60)and hormone group(n=60).The routine group was treated with symptomatic treatment combined with oryzanol tab-lets,and the hormone group was treated with estradiol valerate tablets on the basis of the routine group.The effi-cacy of the two groups was compared.Results After treatment,Kupperman score in hormone group was(12.32±0.89)points,which was lower than(16.56±0.46)points in conventional group,and the difference was statistically significant(t=32.782,P<0.05).The effective rate of hormone group was higher than that of conventional group,and the improvement of hormone level was better than that of conventional group,the differences were statistically sig-nificant(both P<0.05).Conclusion Compared with conventional therapy combined with glutamate tablets,hormone replacement therapy in the treatment of perimenopausal syndrome significantly improves patient symptoms,improves quality of life,and optimizes hormone levels.
Hormone replacement therapyEffective rate of treatmentPerimenopausal syndromeHormone level
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